个人简介

主要研究方向

病毒病检测技术研发及致病机制

主要学术成果

科研项目：   
1.    国家自然科学基金青年项目，31702238，RABV 感染抑制Rac1活性和神经突触功能的机制，2018/01- 2020/12
2.    中国博士后科学基金第62批面上资助二等资助，2017M621215，狂犬病病毒感染致微丝细胞骨架变化的分子机制探究，2018/01- 2019/12
3.    吉林省科技发展计划优秀青年人才基金项目，20180520039JH，RABV感染影响树突棘骨架的机制研究，2018/01-2019/12
4.    吉林省教育厅科学技术研究项目，JJKH20221044KJ，Rho-GTP酶信号通路调控RABV入胞的分子机制研究，2022/01-2023/12
5.    吉林省科技发展计划自然科学基金项目，20220101303JC，泛素化修饰调控RABV感染的分子机制研究，2023/01-2025/12
6.    吉林大学“励新优秀青年教师培养计划” 重点培养阶段，2022/01-2024/12
学术论文：   
1. Xin Guo, Maolin Zhang, Xiaomin Liu, Yannan Zhang, Chongyang Wang and Yidi Guo*. Attachment, Entry, and Intracellular Trafficking of Classical Swine Fever Virus. Viruses. 2023;15:1870.
2. Pengfei Hou#, Yidi Guo#, Hongli Jin#, Jingxuan Sun, Yujie Bai, Wujian Li, Ling Li, Zengguo Cao, Fangfang Wu, Haili Zhang, Yuanyuan Li, Songtao Yang, Xianzhu Xia, Pei Huang, Hualei Wang. Bif-1c Attenuates Viral Proliferation by Regulating Autophagic Flux Blockade Induced by the Rabies Virus CVS-11 Strain in N2a Cells. Microbiol Spectr. 2023; 4: e0307922.
3. Yidi Guo, Xiaohang Yu, Ning Su, Ning Shi, Shu Zhang, Le Zhang, Li Yang, Lili Zhao, Zhenhong Guan, Maolin Zhang, Ming Duan. Identification and characterization of circular RNAs in the A549 cells following Influenza A virus infection. Vet Microbiol. 2022;267:109390.
4. Jing Xu, Jie Gao, Maolin Zhang, Danwei Zhang, Ming Duan, Zhenhong Guan, Yidi Guo*. Dynein- and kinesin- mediated intracellular transport on microtubules facilitates RABV infection. Vet Microbiol. 2021; 262:109241.
5. Ning Shi#, Shu Zhang#, Yidi Guo#, Xiaohang Yu, Weizheng Zhao, Maolin Zhang, Zhenhong Guan, Ming Duan*. CircRNA_0050463 promotes influenza A virus replication by sponging miR-33b-5p to regulate EEF1A1. Vet Microbiol. 2021;254:108995.
6. Yidi Guo, Ming Duan, Xinping Wang, Jie Gao, Zhenhong Guan, Maolin Zhang*. Early events in rabies virus infection-Attachment, entry, and intracellular trafficking. Virus Res. 2019; 263, 217-25.
7. Jie Gao, Xinyu Wang, Mingxin Zhao, Enhua Liu, Ming Duan, Zhenhong Guan, Yidi Guo*, Zhang M*. Entry of Challenge Virus Standard (CVS) -11 into N2a cells via a clathrin-mediated, cholesterol-, dynamin-, pH-dependent endocytic pathway. Virol J. 2019;16(1):80.
8. Yidi Guo#, Waqas Ahmad#, Ying Song, Xinyu Wang, Jie Gao, Ming Duan, Zhenhong Guan, Iahtasham Khan, Muhammad Awais, Maolin Zhang. In vitro Infection of Street and Fixed Rabies Virus Strains Inhibit Gene Expression of Actin Microtubule Binding Proteins EB3 and p140cap in Neurons. Pakistan Veterinary Journal. PAK VET J. 2019; 39(3): 359-64.
9. Xiaoning Sun#, Wenjing Feng#, Yidi Guo#, Qi Wang, Chunyan Dong, Maolin Zhang, Zhenhong Guan, Ming Duan*. MCPIP1 attenuates the innate immune response to influenza A virus by suppressing RIG-Iexpression in lung epithelial cells. J Med Virol. 2018; 90(2):204-11.
10. Waqas Ahmad#, Yingying Li#, Yidi Guo#, Xinyu Wang, Ming Duan, Zhenhong Guan, Zengshan Liu, Maolin Zhang*. Rabies virus co-localizes with early (Rab5) and late (Rab7) endosomal proteins in neuronal and SH-SY5Y cells. Virologica Sinica. 2017; 32(3):207-15.