段铭

吉林大学人兽共患病研究所教授,博士生导师

    职务 主讲人
    时间 地点
    主要研究方向 人兽共患病(病毒) 主要学术成果 科研项目:    在研(主持)
        吉林省自然基金面上项目“宿主长链非编码RNA-NR_002812在甲型流感病毒复制中作用的机制研究(20230101147JC)”
        国家自然基金面上项目 “宿主长链非编码RNA-GBP1P1抑制病毒复制作用的机制研究(31970154)”
    已完成(主持)
        国家自然基金青年基金 “流感病毒感染相关宿主microRNA的鉴定及功能分析(30800823)”
        国家自然基金面上项目 “狂犬病病毒感染相关宿主miRNA的鉴定及功能分析(31172337)”
        “省部共建国家重点实验室开放课题(中国人民解放军军事医学科学院)”
        “吉林大学国家杰出青年基金后备人选培育计划”资助。
    学术论文:    以通讯及第一作者发表的论文
        Guo Y, Yu X, Su N, Shi N, Zhang S, Zhang L, Yang L, Zhao L, Guan Z, Zhang M, Duan M*. Identification and characterization of circular RNAs in the A549 cells following Influenza A virus infection. Vet Microbiol. 2022 Apr;267:109390.
        Shi N, Zhang L, Yu X, Zhu X, Zhang S, Zhang D, Duan M*. Insight Into an Outbreak of Canine Distemper Virus Infection in Masked Palm Civets in China. Front Vet Sci. 2021 Nov 3;8:728238.
        Qi Wang; Daining Zhang; Wenjing Feng; Yidi Guo; Xiaoning Sun; Maolin Zhang; Zhenhong Guan;Ming Duan* Long non‐coding RNA TSPOAP1 antisense RNA 1 negatively modulates type I IFN signaling to facilitate influenza A virus replication. Journal of Medical Virology, 2022 Feb;94(2):557-566.
        Ning Shi#; Shu Zhang#; Yidi Guo#; Xiuhua Yu; Weizheng Zhao; MaolinZhang; Zhenhong Guan; Ming Duan*。CircRNA_0050463 promotes influenza A virus replication by sponging miR-33b-5p to regulate EEF1A1. Veterinary Microbiology. 2021 Mar, (254): 108995.
        Sun xiaoning#; Feng wenjing#; Guo yidi#; Wang Qi; Dong chunyan; Zhang maolin; Guan zhenhong;Duan ming*. MCPIP1 attenuates the innate immune response to influenza A virus by suppressing RIG-I expression in lung epithelial cells. Journal of Medical Virology, 2018, 90(2): 204-211.
        Qu Xinyan#; Ding Xiaoran#;Duan ming#; Yang jing; Lin ruxian; Zhou zhe; Wang shengqi*.Influenza virus infection induces translocation of apoptosis-inducing factor (AIF) in A549 cells: role of AIF in apoptosis and viral propagation. Archives of Virology, 2017, 162(3): 669-675.
        Feng wenjing#; Sun xiaoning#; Shi ning; Zhang maolin; Guan zhenhong;Duan ming*.Influenza a virus NS1 protein induced A20 contributes to viral replication by suppressing interferon-induced antiviral response. Biochemical and Biophysical Research Communications, 2017, 482(4): 1107-1113.
        Dong chunyan; Sun xiaoning; Guan zhenhong; Zhang maolin;Duan ming*.Modulation of influenza A virus replication by microRNA-9 through targeting MCPIP1. Journal of Medical Virology, 2017, 89(1): 41-48.
        Sun xiaoning; Shi ning; Li ying; Dong chunyan; Zhang maolin; Guan zhenhong;Duan ming*.Quantitative Proteome Profiling of Street Rabies Virus-Infected Mouse Hippocampal Synaptosomes. Current Microbiology, 2016, 73(3): 301-311.
        Zhang huanhuan; Yu hongmin; Wang Jiahui; Zhang maolin; Wang X; Ahmad Waqas; Duan ming*; Guan zhenhong*.The BM2 protein of influenza B virus interacts with p53 and inhibits its transcriptional and apoptotic activities. Molecular and Cellular Biochemistry, 2015, 403(1-2): 187-197.
        Zhang Xiaoyang; Dong Chunyan; Sun Xiaoning; Li Zhongyi; Zhang Maolin; Guan Zhenhong;Duan Ming*.Induction of the cellular miR-29c by influenza virus inhibits the innate immune response through protection of A20 mRNA. Biochemical and Biophysical Research Communications, 2014, 450(1): 755-761.
        Shi ning; Zhang xiaoyang; Dong chunyan; Hou jinli; Zhang maolin; Guan zhenhong; Li zhongyi;Duan ming*.Alterations in microRNA expression profile in rabies virus-infected mouse neurons
        Acta Virologica, 2014, 58(2): 120-127.
        Duan ming; Yao honghong; Cai yu; Liao ke; Seth Pankaj; Buch Shilpa*.HIV-1 Tat Disrupts CX3CL1-CX3CR1 Axis in Microglia via the NF-kappa B-YY1 Pathway. Current HIV Research, 2014, 12(3): 189-200.
        Duan ming; Yao honghong; Hu guoku; Chen xianming; Amie K. Lund; Shilpa Buch*.HIV Tat induces expression of ICAM-1 in HUVECs: implications for miR-221/-222 in HIV-associated cardiomyopathy. PLos One, 2013, 8(3): e60170.
        Yao honghong#;Duan ming#; Yang lu; Shilpa Buch*.Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: Involvement of beta 1 integrins. The FASEB Journal,
        Guan zhenhong; Shi ning; Song yan; Zhang xiaoyang; Zhang maolin; Duan ming*.Induction of the cellular microRNA-29c by influenza virus contributes to virus-mediated apoptosis through repression of antiapoptotic factors BCL2L2. Biochemical and Biophysical Research Communications, 2012, 425(3): 662-667.
        Yao honghong#;Duan ming#; Yang lu; Shilpa Buch*.Platelet-Derived Growth Factor-BB Restores Human Immunodeficiency Virus Tat-Cocaine-Mediated Impairment of Neurogenesis: Role of TRPC1 Channels. Journal of Neuroscience, 2012, 32(29): 9835-9847.
        Yao honghong#;Duan ming#; Hu guoku; Shilpa Buch*.Platelet-Derived Growth Factor B Chain Is a Novel Target Gene of Cocaine-Mediated Notch1 Signaling: Implications for HIV-Associated Neurological Disorders. Journal of Neuroscience, 2011, 31(35): 12449-12454.
        Yao honghong#;Duan ming#; Shilpa Buch*.Cocaine-mediated induction of platelet-derived growth factor: implication for increased vascular permeability.Blood, 2011, 117(8): 2538-2547.
    介绍 吉林大学人兽共患病研究所教授,博士生导师
  • 个人简介

    教育经历:

    2003/09 - 2007/06,中国人民解放军军事医学科学院,生物化学与分子生物学,博士。

    1999/09 - 2003/07,原中国人民解放军军需大学,动物营养与饲料科学,硕士。

    1992/09 - 1996/07,中国海洋大学,水产养殖,学士。

    工作经历:

    2016/09 - 至今,吉林大学,人兽共患病研究所,教授

    2010/04 - 2012/04,美国内布拉斯加州医学中心,博士后

    2009/09 - 2016/09,吉林大学,人兽共患病研究所,副教授

    2007/07 - 2009/08,吉林大学,人兽共患病研究所,讲师

    2001/10 - 2004/08,原中国人民解放军军需大学,中心实验室(基因芯片实验室),讲师

    1996/07 - 2001/09,原中国人民解放军军需大学,畜牧兽医学院,助教



  • 主要研究方向

    人兽共患病(病毒)

  • 主要学术成果

    科研项目:    在研(主持)
        吉林省自然基金面上项目“宿主长链非编码RNA-NR_002812在甲型流感病毒复制中作用的机制研究(20230101147JC)”
        国家自然基金面上项目 “宿主长链非编码RNA-GBP1P1抑制病毒复制作用的机制研究(31970154)”
    已完成(主持)
        国家自然基金青年基金 “流感病毒感染相关宿主microRNA的鉴定及功能分析(30800823)”
        国家自然基金面上项目 “狂犬病病毒感染相关宿主miRNA的鉴定及功能分析(31172337)”
        “省部共建国家重点实验室开放课题(中国人民解放军军事医学科学院)”
        “吉林大学国家杰出青年基金后备人选培育计划”资助。
    学术论文:    以通讯及第一作者发表的论文
        Guo Y, Yu X, Su N, Shi N, Zhang S, Zhang L, Yang L, Zhao L, Guan Z, Zhang M, Duan M*. Identification and characterization of circular RNAs in the A549 cells following Influenza A virus infection. Vet Microbiol. 2022 Apr;267:109390.
        Shi N, Zhang L, Yu X, Zhu X, Zhang S, Zhang D, Duan M*. Insight Into an Outbreak of Canine Distemper Virus Infection in Masked Palm Civets in China. Front Vet Sci. 2021 Nov 3;8:728238.
        Qi Wang; Daining Zhang; Wenjing Feng; Yidi Guo; Xiaoning Sun; Maolin Zhang; Zhenhong Guan;Ming Duan* Long non‐coding RNA TSPOAP1 antisense RNA 1 negatively modulates type I IFN signaling to facilitate influenza A virus replication. Journal of Medical Virology, 2022 Feb;94(2):557-566.
        Ning Shi#; Shu Zhang#; Yidi Guo#; Xiuhua Yu; Weizheng Zhao; MaolinZhang; Zhenhong Guan; Ming Duan*。CircRNA_0050463 promotes influenza A virus replication by sponging miR-33b-5p to regulate EEF1A1. Veterinary Microbiology. 2021 Mar, (254): 108995.
        Sun xiaoning#; Feng wenjing#; Guo yidi#; Wang Qi; Dong chunyan; Zhang maolin; Guan zhenhong;Duan ming*. MCPIP1 attenuates the innate immune response to influenza A virus by suppressing RIG-I expression in lung epithelial cells. Journal of Medical Virology, 2018, 90(2): 204-211.
        Qu Xinyan#; Ding Xiaoran#;Duan ming#; Yang jing; Lin ruxian; Zhou zhe; Wang shengqi*.Influenza virus infection induces translocation of apoptosis-inducing factor (AIF) in A549 cells: role of AIF in apoptosis and viral propagation. Archives of Virology, 2017, 162(3): 669-675.
        Feng wenjing#; Sun xiaoning#; Shi ning; Zhang maolin; Guan zhenhong;Duan ming*.Influenza a virus NS1 protein induced A20 contributes to viral replication by suppressing interferon-induced antiviral response. Biochemical and Biophysical Research Communications, 2017, 482(4): 1107-1113.
        Dong chunyan; Sun xiaoning; Guan zhenhong; Zhang maolin;Duan ming*.Modulation of influenza A virus replication by microRNA-9 through targeting MCPIP1. Journal of Medical Virology, 2017, 89(1): 41-48.
        Sun xiaoning; Shi ning; Li ying; Dong chunyan; Zhang maolin; Guan zhenhong;Duan ming*.Quantitative Proteome Profiling of Street Rabies Virus-Infected Mouse Hippocampal Synaptosomes. Current Microbiology, 2016, 73(3): 301-311.
        Zhang huanhuan; Yu hongmin; Wang Jiahui; Zhang maolin; Wang X; Ahmad Waqas; Duan ming*; Guan zhenhong*.The BM2 protein of influenza B virus interacts with p53 and inhibits its transcriptional and apoptotic activities. Molecular and Cellular Biochemistry, 2015, 403(1-2): 187-197.
        Zhang Xiaoyang; Dong Chunyan; Sun Xiaoning; Li Zhongyi; Zhang Maolin; Guan Zhenhong;Duan Ming*.Induction of the cellular miR-29c by influenza virus inhibits the innate immune response through protection of A20 mRNA. Biochemical and Biophysical Research Communications, 2014, 450(1): 755-761.
        Shi ning; Zhang xiaoyang; Dong chunyan; Hou jinli; Zhang maolin; Guan zhenhong; Li zhongyi;Duan ming*.Alterations in microRNA expression profile in rabies virus-infected mouse neurons
        Acta Virologica, 2014, 58(2): 120-127.
        Duan ming; Yao honghong; Cai yu; Liao ke; Seth Pankaj; Buch Shilpa*.HIV-1 Tat Disrupts CX3CL1-CX3CR1 Axis in Microglia via the NF-kappa B-YY1 Pathway. Current HIV Research, 2014, 12(3): 189-200.
        Duan ming; Yao honghong; Hu guoku; Chen xianming; Amie K. Lund; Shilpa Buch*.HIV Tat induces expression of ICAM-1 in HUVECs: implications for miR-221/-222 in HIV-associated cardiomyopathy. PLos One, 2013, 8(3): e60170.
        Yao honghong#;Duan ming#; Yang lu; Shilpa Buch*.Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: Involvement of beta 1 integrins. The FASEB Journal,
        Guan zhenhong; Shi ning; Song yan; Zhang xiaoyang; Zhang maolin; Duan ming*.Induction of the cellular microRNA-29c by influenza virus contributes to virus-mediated apoptosis through repression of antiapoptotic factors BCL2L2. Biochemical and Biophysical Research Communications, 2012, 425(3): 662-667.
        Yao honghong#;Duan ming#; Yang lu; Shilpa Buch*.Platelet-Derived Growth Factor-BB Restores Human Immunodeficiency Virus Tat-Cocaine-Mediated Impairment of Neurogenesis: Role of TRPC1 Channels. Journal of Neuroscience, 2012, 32(29): 9835-9847.
        Yao honghong#;Duan ming#; Hu guoku; Shilpa Buch*.Platelet-Derived Growth Factor B Chain Is a Novel Target Gene of Cocaine-Mediated Notch1 Signaling: Implications for HIV-Associated Neurological Disorders. Journal of Neuroscience, 2011, 31(35): 12449-12454.
        Yao honghong#;Duan ming#; Shilpa Buch*.Cocaine-mediated induction of platelet-derived growth factor: implication for increased vascular permeability.Blood, 2011, 117(8): 2538-2547.