学术论文： |
详情亦请参见： 1）https://www.researchgate.net/profile/Guan-Zhu 2）https://www.ncbi.nlm.nih.gov/myncbi/guan.zhu.1/bibliography/public/ 近10年代表性论文： 1. Liu M, Zhu G (2020) An old drug as a promising new cure for the hard-to-treat echinococcosis. EBioMedicine (Lancet publisher). 55:102749. PMCID: PMC7184152 2. Ma J, Zhang H, Jin Z, Guo F, Geng M, Ju M, Ravichandran A, Orugunty R, Smith L* & Zhu G* (2020) Novel antiparasitic activity of the antifungal lead occidiofungin. Antimicrobial Agents & Chemotherapy. 64(8):e00244-20. PMID: 32457108 3. Yu X, Guo F, Mouneimne RB & Zhu G (2020) Cryptosporidium parvum elongation factor 1α (CpEF1α) participates in the formation of base structure at the infection site during invasion. Journal of Infectious Diseases. 221(11):1816-1825. PMID: 31872225 4. Zhang H & Zhu G (2020). High-Throughput Screening of Drugs Against the Growth of Cryptosporidium parvum In Vitro by qRT-PCR. Methods in Molecular Biology. 2052:319-34. PMID: 31452170 5. Jin Z, Ma J, Zhu G* & Zhang H* (2019). Discovery of Novel Anti-cryptosporidial Activities From Natural Products by in vitro High-Throughput Phenotypic Screening. Frontiers in Microbiology. 10:1999. PMID: 31551955 6. Yu X, Hoyle RL, Guo F, Ratliff CM, Cantu V, Crow J, Xiang L, Heatley JJ & Zhu G (2019). A Vavraia-like microsporidium as the cause of deadly infection in threatened and endangered Eurycea salamanders in the United States. Parasites & Vectors. 12(1):108. PMID: 30871588 7. Guo F, Zhang H, Eltahan R & Zhu G (2019). Molecular and Biochemical Characterization of a Type II Thioesterase From the Zoonotic Protozoan Parasite Cryptosporidium parvum. Frontiers in Cellular & Infection Microbiology. 9:199. PMID: 31231619 8. Eltahan R, Guo F, Zhang H & Zhu G (2019). The Action of the Hexokinase Inhibitor 2-deoxy-d-glucose on Cryptosporidium parvum and the Discovery of Activities against the Parasite Hexokinase from Marketed Drugs. Journal of Eukaryotic Microbiology. 66(3):460-8. PMID: 30222231 9. Guo F, Zhang H, McNair NN, Mead JR & Zhu G (2018). The Existing Drug Vorinostat as a New Lead Against Cryptosporidiosis by Targeting the Parasite Histone Deacetylases. The Journal of Infectious Diseases. 217(7):1110-7. PMID: 29300993 10. Yu X, Zhang H, Zhu G. 2017. Characterization of host cell mutants significantly resistant to Cryptosporidium parvum infection. Journal of Eukaryotic Microbiology. 64(6):843-849. PMID: 28432811. 11. Wang S, Wang S, Luo Y, Xiao L, Luo X, Gao S, Dou Y, Zhang H, Guo A, Meng Q, Hou J, Zhang B, Zhang S, Yang M, Meng X, Mei H, Li H, He Z, Zhu X, Tan X, Zhu XQ, Yu J, Cai J, Zhu G*, Hu S* & Cai X* (2016). Comparative genomics reveals adaptive evolution of Asian tapeworm in switching to a new intermediate host. Nature Communications. 7:12845. PMID: 27653464 12. Ifeonu OO, Chibucos MC, Orvis J, Su Q, Elwin K, Guo F, Zhang H, Xiao L, Sun M, Chalmers RM, Fraser CM, Zhu G, Kissinger JC, Widmer G & Silva JC (2016). Annotated draft genome sequences of three species of Cryptosporidium: Cryptosporidium meleagridis isolate UKMEL1, C. baileyi isolate TAMU-09Q1 and C. hominis isolates TU502_2012 and UKH1. Pathogens & Diseases. 74(7). PMID: 27519257 13. Xiang L, Guo F, Yu Y, Parson LS, LaCoste L, Gibson A, Presley SM, Peterson M, Craig TM, Rollins D, Fedynich AM & Zhu G (2016). Multi-Year Survey of Coccidia, Cryptosporidia, Microsporidia, Histomona and Hematozoa in Wild Quail in the Rolling Plains Ecoregion of Texas and Oklahoma, USA. Journal of Eukaryotic Microbiology. PMID: 27222431 14. Zhang H, Guo F & Zhu G (2015). Cryptosporidium Lactate Dehydrogenase Is Associated with the Parasitophorous Vacuole Membrane and Is a Potential Target for Developing Therapeutics. PLoS Pathogens. 11(11):e1005250. PMID: 26562790 15. Guo F, Ortega-Pierres G, Arguello-Garcia R, Zhang H & Zhu G (2015). Giardia fatty acyl-CoA synthetases as potential drug targets. Frontiers in Microbiology. 6:753. PMID: 26257723 16. Checkley W, White AC, Jr., Jaganath D, Arrowood MJ, Chalmers RM, Chen XM, Fayer R, Griffiths JK, Guerrant RL, Hedstrom L, Huston CD, Kotloff KL, Kang G, Mead JR, Miller M, Petri WA, Jr., Priest JW, Roos DS, Striepen B, Thompson RC, Ward HD, Van Voorhis WA, Xiao L, Zhu G & Houpt ER (2015). A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium. Lancet Infectious Diseases. 15(1):85-94. PMID: 25278220 17. Yu Y, Zhang H, Guo F, Sun M & Zhu G (2014). A unique hexokinase in Cryptosporidium parvum, an apicomplexan pathogen lacking the Krebs cycle and oxidative phosphorylation. Protist. 165(5):701-14. PMID: 25216472 18. Guo F, Zhang H, Fritzler JM, Rider SD, Jr., Xiang L, McNair NN, Mead JR & Zhu G (2014). Amelioration of Cryptosporidium parvum infection in vitro and in vivo by targeting parasite fatty acyl-coenzyme A synthetases. Journal of Infectious Diseases. 209(8):1279-87. PMID: 24273180; PMC3969544. 19. Xiang L, Guo F, Zhang H, LaCoste L, Rollins D, Bruno A, Fedynich AM & Zhu G (2013). Gene discovery, evolutionary affinity and molecular detection of Oxyspirura petrowi, an eye worm parasite of game birds. BMC Microbiology. 13:233. PMID: 24144118; PMC4015439 20. Zhang H, Guo F, Zhou H & Zhu G (2012). Transcriptome analysis reveals unique metabolic features in the Cryptosporidium parvum Oocysts associated with environmental survival and stresses. BMC Genomics. 13:647. PMID: 23171372; PMC3542205 21. Fritzler JM & Zhu G (2012). Novel anti-Cryptosporidium activity of known drugs identified by high-throughput screening against parasite fatty acyl-CoA binding protein (ACBP). Journal of Antimicrobial Chemotherapy. 67(3):609-17. PMID: 22167242; PMC3276058. 22. Fritzler JM, Craig TM, Elgayar A, Plummer C, Wilson RS, Peterson MJ & Zhu G (2011). A new eimeriid (Apicomplexa) species from endangered Attwater's prairie chickens (Tympanuchus cupido attwateri) in Texas. Journal of Parasitology. 97(4):671-5. PMID: 21506827. 23. Zhu G, Shi X & Cai X (2010). The reductase domain in a Type I fatty acid synthase from the apicomplexan Cryptosporidium parvum: restricted substrate preference towards very long chain fatty acyl thioesters. BMC Biochemistry. 11:46. PMID: 21092192; PMC2995488 24. Yu Y, Zhang H & Zhu G (2010). Plant-type trehalose synthetic pathway in cryptosporidium and some other apicomplexans. PLoS One. 5(9):e12593. PMID: 20830297; PMC2935371 25. Templeton TJ, Enomoto S, Chen WJ, Huang CG, Lancto CA, Abrahamsen MS & Zhu G (2010). A genome-sequence survey for Ascogregarina taiwanensis supports evolutionary affiliation but metabolic diversity between a Gregarine and Cryptosporidium. Molecular Biology and Evolution. 27(2):235-48. PMID: 19778951; PMC2877549. 26. Rider SD, Jr. & Zhu G (2010). Cryptosporidium: genomic and biochemical features. Experimental Parasitology. 124(1):2-9. PMID: 19187778; PMC2819285 27. Lei C, Rider SD, Jr., Wang C, Zhang H, Tan X & Zhu G (2010). The apicomplexan Cryptosporidium parvum possesses a single mitochondrial-type ferredoxin and ferredoxin:NADP+ reductase system. Protein Science. 19(11):2073-84. PMID: 20737579; PMC3005779 |
